The episodic film tells the stories and experiences of different people in the city of Zurich on a Friday night. People who don't know each other meet at six different locations. Two young unemployed men want to rob a bar, Swiss and Germans play cards at a regulars' table, a Zurich scene-goer tries to overcome his inability to form relationships with the help of a psychologist, and a banker cheats on his wife. Characters who are initially characterized as clichés gradually gain depth and become human. "Nachtexpress" shows encounters that could happen every night in Swiss cities. People get together to drink, talk, argue, and love. "Nachtexpress" is a socially critical comedy—a folk play that deals with current issues such as latent racism, love, and inconsistency.