Enemmy follows daredevil CID officers against an underworld don. Four under cover cops Eklavya (Sunil Shetty), Naeem (Kay Kay Menon), Madhav (Mahaakshay Chakraborty) and Eric (Johny Lever) get the assignment to stop a gang war over a missing sum of money. They manage to put under world don Mukhtar Memon (Zakir Hussain) behind the bars but that doesn't solve the problem. Later, a senior CBI officer Yugandhar (Mithun Chakraborty) starts investigating the case