UFC on ESPN 1: Ngannou vs. Velasquez was a mixed martial arts event produced by the Ultimate Fighting Championship that was held on February 17, 2019 at Talking Stick Resort Arena, now known as Footprint Center in Phoenix, Arizona, United States. A heavyweight bout between former two-time UFC Heavyweight Champion Cain Velasquez and former title challenger Francis Ngannou served as the event headliner.